Urge urinary incontinence (UI) is defined as the unwanted urine leakage that happens shortly after the sudden, intense desire to urinate. Urge UI is caused by involuntary bladder contractions that occur as your bladder fills. Occurs when nerve passages along the pathway from the bladder to the brain are damaged, causing a sudden bladder contraction that cannot be consciously inhibited. Urine loss is usually in large amounts that soak underwear and even outer clothing. Stroke, dementia, Alzheimer’s Disease, and Multiple Sclerosis (MS) can all cause urge incontinence. Urge Incontinence is a major symptom of Over Active Bladder (OAB).